This tutorial shows an example of the
serocalculator R package, developed by the
SeroEpidemiology Research Group (SERG) at UC Davis. Here, we show users how to use the package to estimate seroincidence of enteric fever from cross-sectional serologic surveys. Further details on the methodology and use of the package can be found at
https://ucd-serg.github.io/serocalculator/.
Serocalculator is available on
CRAN and
GitHub. Data used in this example as well as additional longitudinal seroresponse parameters can be found in the our
Open Science Framework Data Repository.
This project was supported by grants from the National Institutes of Health (NIH) National Institute of Allergy and Infectious Disease (R21AI176416), the NIH Fogarty International Center (K01TW012177) and the Bill and Melinda Gates Foundation. We gratefully acknowledge the study participants for their valuable time and interest in participating in these studies. Special thanks to our collaborators at Sabin Vaccine Institute, Aga Khan University (Karachi, Pakistan), Child Health Research Foundation (Dhaka, Bangladesh), and Dhulikhel Hospital, Kathmandu University Hospital (Dhulikhel, Nepal).
